Induction of cytochrome P-450 in the rat liver after exposure to xylenes, dose-response relationship and dependence on endocrine factors

Author:

Toftgård Rune,Nilsen Odd G.,Glaumann Hans,Gustafsson Jan-Åke

Publisher

Elsevier BV

Subject

Toxicology

Reference38 articles.

1. The combined toxicity of technical grade xylene and ethanol in the rat;Elovaara;Xenobiotica,1980

2. Changes in rat liver microsomal cytochrome P-450 and enzymatic activities after the inhalation of n-hexane, xylene, methyl ethyl ketone and methylchloroform for four weeks;Toftgård;Scand. J. Work Environ. Health,1981

3. Effects of xylene and xylene isomers on cytochrome P-450 and in vitro enzymatic activities in rat liver and lung;Toftgård;Toxicology,1982

4. Xylene induces a cytochrome P-450 isozyme in rat liver similar to the major isozyme induced by phenobarbital;Toftgård;Mol. Pharmacol.,1983

5. Cytochrome P-450 dependent covalent binding of 1,1,2,2-tetrachloroethane in vitro;Halpert;Drug Metab. Dispos.,1982

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