Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation-Reference-Cited by-同舟云学术

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Characterization of a human and murine mPGES-1 inhibitor and comparison to mPGES-1 genetic deletion in mouse models of inflammation

Published:2013-12 Issue: Volume:107 Page:26-34
ISSN:1098-8823
Container-title:Prostaglandins & Other Lipid Mediators
language:en
Short-container-title:Prostaglandins & Other Lipid Mediators

Author:

Leclerc Patrick,Idborg Helena,Spahiu Linda,Larsson Charlotte,Nekhotiaeva Natalia,Wannberg Johan,Stenberg Patric,Korotkova Marina,Jakobsson Per-Johan

Publisher

Elsevier BV

Subject

Cell Biology,Pharmacology,Physiology,Biochemistry

Reference28 articles.

1. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target;Jakobsson;Proc Natl Acad Sci USA,1999

2. Expression of microsomal prostaglandin E synthase 1 in rheumatoid arthritis synovium;Westman;Arthritis Rheum,2004

3. Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis;Korotkova;Ann Rheum Dis,2008

4. Clinical significance of prostaglandin E synthase expression in gastric cancer tissue;Gudis;Hum Pathol,2007

5. Lipopolysaccharide-dependent prostaglandin E-2 production is regulated by the glutathione-dependent prostaglandin E-2 synthase gene induced by the toll-like receptor 4/MyD88/NF-IL6 pathway;Uematsu;J Immunol,2002

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4. The anti-inflammatory and vasoprotective properties of mPGES-1 inhibition offer promising therapeutic potential;Expert Opinion on Therapeutic Targets;2023-11-02

5. Microsomal prostaglandin E synthase-1 inhibition promotes shunting in arachidonic acid metabolism during inflammatory responses in vitro;Prostaglandins & Other Lipid Mediators;2023-08

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