BM-520, an original TXA2 modulator, inhibits the action of thromboxane A2 and 8-iso-prostaglandin F2α in vitro and in vivo on human and rodent platelets, and aortic vascular smooth muscles from rodents

Author:

Rolin S.,Hanson J.,Vastersaegher C.,Cherdon C.,Pratico D.,Masereel B.,Dogne J.M.

Publisher

Elsevier BV

Subject

Cell Biology,Pharmacology,Physiology,Biochemistry

Reference43 articles.

1. Thromboxane synthase: structure and function of protein and gene;Wang;Prostaglandins Other Lipid Mediat,2002

2. Cloning and expression of cDNA for a human thromboxane A2 receptor;Hirata;Nature,1991

3. Cell signalling through thromboxane A2 receptors;Huang;Cell Signal,2004

4. Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin;Moncada;Pharmacol Rev,1978

5. Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction;Gurbel;Prostaglandins Leukot Essent Fatty Acids,1999

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