Low-dose immune tolerance induction therapy in severe hemophilia a children in China: Starting earlier resulted in better inhibitor eradication outcomes

Author:

Li ZhengpingORCID,Sun Jie,Li Zekun,Chen Zhenping,Liu Guoqing,Yao Wanru,Li Gang,Zhen Yingzi,Cheng Xiaoling,Ai Di,Huang Kun,Poon Man-ChiuORCID,Wu RunhuiORCID

Funder

National Natural Science Foundation of China

Capital Health Research and Development of Special Fund

Publisher

Elsevier BV

Subject

Hematology

Reference28 articles.

1. A randomized trial of factor VIII and neutralizing antibodies in hemophilia A;Peyvandi;N. Engl. J. Med.,2016

2. Timing of inhibitor development in more than 1000 previously untreated patients with severe hemophilia A;van den Berg;Blood,2019

3. Outcomes in children with hemophilia A with inhibitors: results from a noninterventional study;Oldenburg;Pediatr. Blood Cancer,2020

4. Hemophilia A with inhibitor: immune tolerance induction (ITI) in the mirror of time;Nakar;Transfus. Apher. Sci.,2019

5. Immune tolerance for the treatment of factor VIII inhibitors–twenty years' 'Bonn protocol';Brackmann;Vox Sang.,1996

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