The R306G and R506Q mutations in coagulation Factor V reveals additional cleavage sites for Activated Protein C in the R313-R321 region and at R505
Author:
Publisher
Elsevier BV
Subject
Hematology
Reference34 articles.
1. Factor V: a combination of Dr Jekyll and Mr Hyde;Mann;Blood,2003
2. Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders;Kane;Blood,1988
3. Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa;Shen;J Biol Chem,1994
4. The reassociation of factor Va from its isolated subunits;Krishnaswamy;J Biol Chem,1989
5. A plausible mechanism for prothrombin activation by factor Xa, factor Va, phospholipid, and calcium ions;Esmon;J Biol Chem,1974
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