Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis-Reference-Cited by-同舟云学术

Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis

Published:2009-11 Issue:5 Volume:124 Page:565-571
ISSN:0049-3848
Container-title:Thrombosis Research
language:en
Short-container-title:Thrombosis Research

Author:

van Giezen J.J.J.,Berntsson Pia,Zachrisson Helen,Björkman Jan-Arne

Publisher

Elsevier BV

Subject

Hematology

Reference14 articles.

1. Preclinical and clinical studies with selective reversible direct P2Y12 antagonists;van Giezen;Semin Thromb Haemost,2005

2. From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis;Springthorpe;Bioorg Med Chem Lett,2007

3. Direct oral P2Y12 receptor antagonist AZD6140 potently and reversibly binds to the rh-P2Y12 receptor expressed on CHO-K1 cells;van Giezen;Arterioscler Thromb Vasc Biol,2008

4. Single dose pharmacokinetics and pharmacodynamics of AZD6140;Peters;Haematologica,2004

5. Multiple-dose pharmacokinetics (PK) and pharmacodynamics (PD) of the oral reversible, orally active ADP receptor antagonist AZD6140;Peters;Eur Heart J,2006

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