CSF/plasma HIV-1 RNA discordance even at low levels is associated with up-regulation of host inflammatory mediators in CSF

Author:

Nightingale Sam,Michael Benedict D.,Fisher Martin,Winston Alan,Nelson Mark,Taylor Steven,Ustianowski Andrew,Ainsworth Jonathan,Gilson Richard,Haddow Lewis,Ong Edmund,Leen Clifford,Minton Jane,Post Frank,Beloukas Apostolos,Borrow Ray,Pirmohamed Munir,Geretti Anna Maria,Khoo Saye,Solomon Tom

Publisher

Elsevier BV

Subject

Molecular Biology,Hematology,Biochemistry,Immunology,Immunology and Allergy

Reference27 articles.

1. Factors associated with cerebrospinal fluid HIV RNA in HIV infected subjects undergoing lumbar puncture examination in a clinical setting;Rawson;J. Infect.,2012

2. HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment;Eden;J. Infect. Dis.,2010

3. S. Letendre, D. McClemon, R. Ellis, et al. Persistent HIV in the Central Nervous System during Treatment is Associated with Worse ART Penetration and Cognitive Impairment. Paper #484b 16th Conference on Retroviruses and Opportunistic Infections (CROI 2009), Montreal, Canada, 2009.

4. Prevalence and risk factors for HIV CSF Viral Escape: results from the CHARTER and HNRP cohorts;Perez-Valero;J. Int. AIDS Soc.,2012

5. Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy;Canestri;Clin. Infect. Dis.: Off. Publ. Infect. Dis. Soc. Am.,2010

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