A new approach to the role of IL-7 and TGF-ß in the in vitro generation of thymus-derived CD4+CD25+Foxp3+ regulatory T cells

Author:

Bieńkowska Anna,Kiernozek Ewelina,Kozlowska Ewa,Bugajski Łukasz,Drela Nadzieja

Funder

Polish Ministry of Science and Higher Education

Warsaw University Intramural

Publisher

Elsevier BV

Subject

Molecular Biology,Hematology,Biochemistry,Immunology,Immunology and Allergy

Reference30 articles.

1. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state;Takahashi;Int. Immunol.,1998

2. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J. Immunol.,1995

3. Regulatory T cells and immune tolerance;Sakaguchi;Cell,2008

4. Nature and nurture in Foxp3(+) regulatory T cell development, stability, and function;Geiger;Hum. Immunol.,2012

5. Distinct regulatory roles of transforming growth factor-beta and interleukin-4 in the development and maintenance of natural and induced CD4+ CD25+ Foxp3+ regulatory T cells;Prochazkova;Immunology,2009

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