Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling-Reference-Cited by-同舟云学术

Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling

Published:2019-06 Issue: Volume:118 Page:144-159
ISSN:1043-4666
Container-title:Cytokine
language:en
Short-container-title:Cytokine

Author:

Raj Vinit,Bhadauria Archana S.,Singh Ashok K.,Kumar Umesh,Rai Amit,Keshari Amit K.,Kumar Pranesh,Kumar Dinesh,Maity Biswanath,Nath Sneha,Prakash Anand,Ansari Kausar M.,Jat Jawahar L.,Saha Sudipta

Publisher

Elsevier BV

Subject

Molecular Biology,Hematology,Biochemistry,Immunology,Immunology and Allergy

Reference61 articles.

1. Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis;Xu;Food Chem. Toxicol.,2010

2. A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2;Iguchi;Cancer Lett.,2009

3. Orthotopic implantation of a colon cancer xenograft induces high expression of cyclooxygenase-2;Shoji;Cancer Lett.,2003

4. The IL-6/JAK/STAT3 pathway: potential therapeutic strategies in treating colorectal cancer;Wang;Int. J. Oncol.,2014

5. Chemopreventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on 1, 2-dimethylhydrazine-induced rat colon carcinogenesis;Wei;Cancer Lett.,2003

Cited by 31 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Inhibition of NF-kB and COX-2 by andrographolide regulates the progression of cervical cancer by promoting PTEN expression and suppressing PI3K/AKT signalling pathway;Scientific Reports;2024-05-26

2. Synthesis of flaxseed gum/melanin-based scaffold: A novel approach for nano-encapsulation of doxorubicin with enhanced anticancer activity;International Journal of Biological Macromolecules;2024-01

3. The Protective Effects of Silymarin on the Reproductive Toxicity: A Comprehensive Review;Current Medicinal Chemistry;2023-12

4. Prospects of new targeted nanotherapy combining liponiosomes with berberine to combat colorectal cancer development: An in vivo experimental model;International Journal of Pharmaceutics;2023-11

5. The Radioprotective Potentials of Silymarin/Silibinin Against Radiotherapy- Induced Toxicities: A Systematic Review of Clinical and Experimental Studies;Current Medicinal Chemistry;2023-10