Ablation of the CD9 receptor in human lung cancer cells using CRISPR/Cas alters migration to chemoattractants including IL-16

Author:

Blake David J.,Martiszus Jonathon D.,Lone Tia H.,Fenster Steven D.

Funder

Fort Lewis CollegeFort Lewis College (DB)

Faculty Development Grant for Teaching, Innovation and Pedagogy at Fort Lewis CollegeFaculty Development Grant for Teaching, Innovation and Pedagogy at Fort Lewis College (DB and SF)

Minority Access to Research Careers – Undergraduate Student Training in Academic Research

Publisher

Elsevier BV

Subject

Molecular Biology,Hematology,Biochemistry,Immunology,Immunology and Allergy

Reference13 articles.

1. Soluble extracellular Klotho decreases sensitivity to cigarette smoke induced cell death in human lung epithelial cells;Blake;Toxicol. In Vitro,2015

2. Lymphocyte chemoattractant factor induces CD4-dependent intracytoplasmic signaling in lymphocytes;Cruikshank;J. Immunol.,1991

3. The role of CD4-dependent signaling in interleukin-16 induced c-Fos expression and facilitation of neurite outgrowth in cerebellar granule neurons;Fenster;Neurosci. Lett.,2010

4. Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB;Jang;Biochem. Biophys. Res. Commun.,2004

5. IL-16 activates the SAPK signaling pathway in CD4+ macrophages;Krautwald;J. Immunol.,1998

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