Study on fluorination-toxicity relationships. Syntheses of 1-N-[(2R,3R)- and (2R,3S)-4-amino-3-fluoro-2-hydroxybutanoyl] derivatives of kanamycins
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Biochemistry,General Medicine,Analytical Chemistry
Reference25 articles.
1. Syntheses of 3-fluoro derivatives of sporaricin A, 3-epifluoro-, 3-fluoro, and 3,3-difluoro-3-demethoxysporaricin A.
2. Syntheses of 3-fluoro-, 3-epi-3-fluoro-, and 3,3-difluoro-3-de(methoxy)sporaricin A
3. Synthesis of 3'-deoxy-3'-fluorokanamycins A and B active against resistant bacteria.
4. Study on fluorination of 2,3-dideoxy-2,3-(N-tosylepimino)-α-d-allopyranosides, and synthesis of 3′-deoxy-3′-fluoro-kanamycin B and 3′,4′-dideoxy-3′-fluoroakanamycin B
5. Synthesis of 5-deoxy-5-fluoro and 5-deoxy-5,5-difluoro derivatives of kanamycin B in its analogs. Study on structure-toxicity relationships
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