Resolution of racemic flurbiprofen by lipase-mediated esterification in organic solvent
Author:
Publisher
Elsevier BV
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis
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1. Aspirin-like drugs may block pain independently of prostaglandin synthesis inhibition
2. Rac-Flurbiprofen is more ulcerogenic than its (S)-enantiomer
3. Antinociceptive actions of R(−)-flurbiprofen - a non-cyclooxygenase inhibiting 2-arylpropionic acid - in rats
4. Drug Chirality: On the Mechanism of R-Aryl Propionic Acid Class NSAIDs. Epimerization in Humans and the Clinical Implications for the Use of Racemates
5. A facile enzymatic resolution process for the preparation of (+)--2-(6-hethoxy-2-naphthyl)propionic acid (Naproxen).
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