Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets-Reference-Cited by-同舟云学术

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Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Published:2019-03 Issue:5 Volume:73 Page:885-899.e6
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Mengwasser Kristen E.,Adeyemi Richard O.,Leng Yumei,Choi Mei Yuk,Clairmont Connor,D’Andrea Alan D.,Elledge Stephen J.

Funder

National Institute of General Medical Sciences

Breast Cancer Research Foundation

NCI

DOD

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference59 articles.

1. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response;Adamson;Nat. Cell Biol.,2012

2. A method and server for predicting damaging missense mutations;Adzhubei;Nat. Methods,2010

3. Flap endonuclease 1;Balakrishnan;Annu. Rev. Biochem.,2013

4. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair;Bennardo;PLoS Genet.,2008

5. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2;Bhatia;Nature,2014

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2. Endogenous base damage as a driver of genomic instability in homologous recombination-deficient cancers;DNA Repair;2024-09

3. "Bridging the DNA divide": Understanding the interplay between replication- gaps and homologous recombination proteins RAD51 and BRCA1/2;DNA Repair;2024-09

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