Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability
Author:
Funder
NIH
Department of Defense
Life Sciences Research Foundation
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference47 articles.
1. A tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1;Bar-Peled;Science,2013
2. Longin and GAF domains: structural evolution and adaptation to the subcellular trafficking machinery;De Franceschi;Traffic,2014
3. Signal integration by mTORC1 coordinates nutrient input with biosynthetic output;Dibble;Nat. Cell Biol.,2013
4. Nutrient-sensing mechanisms and pathways;Efeyan;Nature,2015
5. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP;Feig;Mol. Cell. Biol.,1988
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