Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1-Reference-Cited by-同舟云学术

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Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1

Published:2019-11 Issue:4 Volume:76 Page:562-573.e4
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Chung Mingyu,Liu Chad,Yang Hee Won,Köberlin Marielle S.,Cappell Steven D.,Meyer Tobias

Funder

Stanford Center for Systems Biology

Damon Runyon Cancer Research Foundation

National Institute of General Medical Sciences

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference44 articles.

1. Cdc2-cyclin E complexes regulate the G1/S phase transition;Aleem;Nat. Cell Biol.,2005

2. A dynamical framework for the all-or-none G1/S transition;Barr;Cell Syst.,2016

3. Irreversible APC(Cdh1) inactivation underlies the point of no return for cell-cycle entry;Cappell;Cell,2016

4. EMI1 switches from being a substrate to an inhibitor of APC/CCDH1 to start the cell cycle;Cappell;Nature,2018

5. Spectrum and degree of CDK drug interactions predicts clinical performance;Chen;Mol. Cancer Ther.,2016

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