Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation

Author:

Mitchener Michelle M.,Muir Tom W.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference125 articles.

1. The H3.3K27M oncohistone antagonizes reprogramming in Drosophila;Ahmad;PLoS Genet.,2021

2. Cancer-associated mutations of histone H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome;Arimura;Nucleic Acids Res.,2018

3. Oncohistone mutations enhance chromatin remodeling and alter cell fates;Bagert;Nat. Chem. Biol.,2021

4. Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone;Behjati;Nat. Genet.,2013

5. Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas;Bender;Cancer Cell,2013

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