Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB-Reference-Cited by-同舟云学术

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Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Published:2006-04 Issue:2 Volume:22 Page:159-168
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Sarbassov Dos D.,Ali Siraj M.,Sengupta Shomit,Sheen Joon-Ho,Hsu Peggy P.,Bagley Alex F.,Markhard Andrew L.,Sabatini David M.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference45 articles.

1. Mechanism of activation of protein kinase B by insulin and IGF-1;Alessi;EMBO J.,1996

2. Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site;Ali;J. Biol. Chem.,2005

3. A mammalian protein targeted by G1-arresting rapamycin-receptor complex;Brown;Nature,1994

4. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor;Brunet;Cell,1999

5. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1;Burnett;Proc. Natl. Acad. Sci. USA,1998

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