Insights into Lysosomal PI(3,5)P2 Homeostasis from a Structural-Biochemical Analysis of the PIKfyve Lipid Kinase Complex
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference28 articles.
1. Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase;Botelho;Mol. Biol. Cell,2008
2. Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J;Chow;Nature,2007
3. Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS;Chow;Am. J. Hum. Genet.,2009
4. APP controls the formation of PI(3,5)P(2) vesicles through its binding of the PIKfyve complex;Currinn;Cell. Mol. Life Sci.,2016
5. Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels;Duex;Eukaryot. Cell,2006
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