Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency-Reference-Cited by-同舟云学术

Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency

Published:2021-08 Issue:15 Volume:81 Page:3128-3144.e7
ISSN:1097-2765
Container-title:Molecular Cell
language:en
Short-container-title:Molecular Cell

Author:

Cong Ke,Peng Min,Kousholt Arne Nedergaard,Lee Wei Ting C.,Lee Silviana,Nayak Sumeet,Krais John,VanderVere-Carozza Pamela S.,Pawelczak Katherine S.,Calvo Jennifer,Panzarino Nicholas J.,Turchi John J.,Johnson Neil,Jonkers Jos,Rothenberg Eli,Cantor Sharon B.

Funder

Fanconi Anemia Research Fund

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference129 articles.

1. CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers;Adam;bioRxiv,2021

2. Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease;Álvarez-Quilón;Mol. Cell,2020

3. Radiation-induced mitotic catastrophe in PARG-deficient cells;Amé;J. Cell Sci.,2009

4. Alternative Okazaki Fragment Ligation Pathway by DNA Ligase III;Arakawa;Genes (Basel),2015

5. p53 and p21 regulate error-prone DNA repair to yield a lower mutation load;Avkin;Mol. Cell,2006

Cited by 170 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. "Bridging the DNA divide": Understanding the interplay between replication- gaps and homologous recombination proteins RAD51 and BRCA1/2;DNA Repair;2024-09

2. Human translesion DNA polymerases ι and κ mediate tolerance to temozolomide in MGMT-deficient glioblastoma cells.;DNA Repair;2024-09

3. (Single-stranded DNA) gaps in understanding BRCAness;Trends in Genetics;2024-09

4. PARPi, BRCA, and gaps: controversies and future research;Trends in Cancer;2024-09

5. DNA polymerase α-primase facilitates PARP inhibitor-induced fork acceleration and protects BRCA1-deficient cells against ssDNA gaps;Nature Communications;2024-08-27