Nuclear destruction: A suicide mission by AKIRIN2 brings intact proteasomes into the nucleus
Author:
Funder
National Institutes of Health
National Cancer Institute
Council for Chemical Research
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference10 articles.
1. The Sts1 nuclear import adapter uses a non-canonical bipartite nuclear localization signal and is directly degraded by the proteasome;Budenholzer;J. Cell Sci.,2020
2. Sts1 plays a key role in targeting proteasomes to the nucleus;Chen;J. Biol. Chem.,2011
3. Proteasome interaction with ubiquitinated substrates: from mechanisms to therapies;Chen;FEBS J.,2021
4. AKIRIN2 controls the nuclear import of proteasomes in vertebrates;de Almeida;Nature,2021
5. Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in drosophila and mice;Goto;Nat. Immunol.,2008
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