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PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression

  • Published:2019-08 Issue:3 Volume:75 Page:620-630.e9
  • ISSN:1097-2765
  • Container-title:Molecular Cell
  • language:en
  • Short-container-title:Molecular Cell

Author:

Sendinc Erdem,Valle-Garcia David,Dhall Abhinav,Chen Hao,Henriques Telmo,Navarrete-Perea Jose,Sheng Wanqiang,Gygi Steven P.,Adelman Karen,Shi Yang

Funder

NIH

Boston Children's Hospital

Harvard Medical School

NSF

CONACyT

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology

Reference27 articles.

1. Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase;Akichika;Science,2019

2. Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control;Barbieri;Nature,2017

3. A probability-based approach for high-throughput protein phosphorylation analysis and site localization;Beausoleil;Nat. Biotechnol.,2006

4. Identification of the m6Am methyltransferase PCIF1 reveals the location and functions of m6Am in the transcriptome;Boulias;bioRxiv,2018

5. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq;Dominissini;Nature,2012

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