Synthesis and X-ray crystal structure of the calcium channel antagonist: dimethyl 1,4-dihydro-2,6-dimethyl-4-[4′-(4H-4-oxo-1-benzopyran-2-yl)phenyl]-3,5-pyridine dicarboxylate

Author:

Tunçbilek Meral,Özbey Süheyla,Kendi Engin,Yıldırım Engin,Erol Kevser,Ertan Rahmiye

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmaceutical Science

Reference28 articles.

1. Wilson and Gisvold’s Texbook of Organic Medicinal and Pharmaceutical Chemistry;Delgado,1991

2. Conformational features of calcium channel agonist and antagonist analogs of nifedipine;Langs;J. Mol. Pharmacol.,1985

3. Qsar of binding of dihydropyridine-type calcium antagonists to their receptor on ileal smooth muscle preparations;Mahmoudian;J. Pharm. Pharmacol.,1986

4. Receptor binding properties of the new calcium antagonist benidipine hydrochloride;Ishii;Arzneim.-Forsch./Drug Res.,1988

5. Active conformation of 1,4-dihydropyridine calcium entry blockers. Effect of size of 2-aryl substituent on rotameric equilibria and receptor binding;Rovnyak;J. Med. Chem.,1991

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