Functional assays for BRCA1 and BRCA2
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Biochemistry
Reference92 articles.
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2. Large genomic deletions inactivate the BRCA2 gene in breast cancer families;Agata;J. Med. Genet.,2005
3. The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity;Baer;Curr. Opin. Genet. Dev.,2002
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5. BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer;Bochar;Cell,2000
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1. BRCA1, BRCA2, and TP53 germline and somatic variants and clinicopathological characteristics of Brazilian patients with epithelial ovarian cancer;Cancer Medicine;2024-02
2. BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair;eLife;2022-09-13
3. BRCA1/2 variants of unknown significance in hereditary breast and ovarian cancer (HBOC) syndrome: Looking for the hidden meaning;Critical Reviews in Oncology/Hematology;2022-04
4. Cancer missense mutations in the BRC repeats of BRCA2 protein disrupt RAD51 binding and activity leading to chemotherapeutic sensitivity;2021-09-25
5. Imprecise Medicine: BRCA2 Variants of Uncertain Significance (VUS), the Challenges and Benefits to Integrate a Functional Assay Workflow with Clinical Decision Rules;Genes;2021-05-20
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