FLT-3: a new focus in the understanding of acute leukemia

Author:

Markovic Ana,MacKenzie Karen L.,Lock Richard B.

Publisher

Elsevier BV

Subject

Cell Biology,Biochemistry

Reference21 articles.

1. Inhibition of FLT3 in MLL: validation of a therapeutic target identified by gene expression based classification;Armstrong;Cancer Cell,2003

2. A phase I study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease;Fiedler;Blood (First Edition Paper),2004

3. SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes;Giles;Blood,2003

4. The roles of FLT3 in hematopoiesis and leukemia;Gilliland;Blood,2002

5. Phosphatidylinositol 3-kinase is essential for kit ligand-mediated survival, whereas interleukin-3 and flt3 ligand induce expression of antiapoptotic Bcl-2 family genes;Karlsson;Journal of Leukocyte Biology,2003

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