Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism-Reference-Cited by-同舟云学术

Akt is upstream and MAPKs are downstream of NF-κB in paclitaxel-induced survival signaling events, which are down-regulated by curcumin contributing to their synergism

Published:2011-03 Issue:3 Volume:43 Page:331-341
ISSN:1357-2725
Container-title:The International Journal of Biochemistry & Cell Biology
language:en
Short-container-title:The International Journal of Biochemistry & Cell Biology

Author:

Bava Smitha V.,Sreekanth Chanickal N.,Thulasidasan Arun Kumar T.,Anto Nikhil P.,Cheriyan Vino T.,Puliyappadamba Vineshkumar T.,Menon Sajna G.,Ravichandran Santhosh D.,Anto Ruby John

Funder

Department of Biotechnology, Government of India

Publisher

Elsevier BV

Subject

Cell Biology,Biochemistry

Reference41 articles.

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2. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation;Aggarwal;Mol Pharmacol,2006

3. Transient stimulation of the c-Jun-NH2-Terminal Kinase/Activator Protein 1 pathway and inhibition of extracellular signal-regulated kinase are early effects in paclitaxel-mediated apoptosis in human B lymphoblasts;Amato;Cancer Res,1998

4. L-929 cells harboring ectopically expressed RelA resist curcumin-induced apoptosis;Anto;J Biol Chem,2000

5. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl;Anto;Carcinogenesis,2002

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