Inhibitor of pan class-I PI3K induces differentially apoptotic pathways in acute leukemia cells: Shedding new light on NVP-BKM120 mechanism of action
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Biochemistry
Reference35 articles.
1. The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia;Allegretti;Sci. Rep.,2015
2. Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM;Alonso;Blood,2009
3. The phosphatidylinositol‐3 kinase I inhibitor BKM120 induces cell death in B‐chronic lymphocytic leukemia cells in vitro;Amrein;Int. J. Cancer,2013
4. Targeting the PI3K/AKT/mTOR signaling axis in children with hematologic malignancies;Barrett;Pediatric Drugs,2012
5. The catalytic PI3 K isoforms p110γ and p110δ contribute to B cell development and maintenance, transformation, and proliferation;Beer-Hammer;J. Leukoc. Biol.,2010
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