Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro

Author:

Ribeiro Diego Luís,Machado Ana Rita Thomazela,da Silva Machado Carla,Santos Patrick Wellington da Silva,Aissa Alexandre Ferro,Barcelos Gustavo Rafael MazzaronORCID,Antunes Lusânia Maria Greggi

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil

São Paulo Foundation Research

National Council for Scientific and Technological Development (CNPq

Publisher

Elsevier BV

Subject

Toxicology

Reference71 articles.

1. Phytochemical compounds in sport nutrition: synephrine and hydroxycitric acid (HCA) as examples for evaluation of possible health risks;Bakhiya;Mol. Nutr. Food Res.,2017

2. Guidance on good cell culture practice (GCCP);Bal-price,2011

3. Ischemic stroke associated with use of an ephedra-free dietary supplement containing synephrine;Bouchard;Mayo Clin. Proc.,2005

4. Effects of amphetamines on mitochondrial function: role of free radicals and oxidative stress;Brown;Pharmacol. Ther.,2003

5. Gilman’s the Pharmacological Basis of Therapeutics;Brunton,2005

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