Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyrimidine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis-Reference-Cited by-同舟云学术

Synthesis and evaluation of hydrazinyl-containing pyrrolo[2,3-d]pyrimidine series as potent, selective and oral JAK1 inhibitors for the treatment of rheumatoid arthritis

Published:2022-10 Issue: Volume:74 Page:128905
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Mao Weiwei,Wu Hao,Guo Qiang,Zheng Xuejian,Wei Changqing,Liao Yonggang,Shen Liang,Mi Jingyu,Li Jian,Chen Shuhui,Qian Wenyuan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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5. Jakinibs: a new class of kinase inhibitors in cancer and autoimmune disease;Kontzias;Curr Opin Pharmacol.,2012

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