Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent-Reference-Cited by-同舟云学术

Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent

Published:2021-11 Issue: Volume:52 Page:128327
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Jiang Tian,Jaunky Dilan B.,Larocque Kevin,Chen Fei,Mckibbon Keegan,Sirouspour Mehdi,Taylor Sarah,Shafeii Alexandre,Campbell Donald,Braga Helena,Piekny Alisa,Forgione Pat

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference43 articles.

1. Paclitaxel-resistant cells have a mutation in the paclitaxel-binding region of beta-tubulin (Asp26Glu) and less stable microtubules;Hari;Mol Cancer Ther,2006

2. Microtubules and resistance to tubulin-binding agents;Kavallaris;Nat Rev Cancer,2010

3. Hallmarks of cancer: the next generation;Hanahan;Cell,2011

4. Microtubule-binding agents: a dynamic field of cancer therapeutics;Dumontet;Nat Rev Drug Discov,2010

5. Mitosis-targeted anti-cancer therapies: where they stand;Chan;Cell Death Dis,2012

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Thieno[2,3‐c]isoquinolines: A novel chemotype of antiproliferative agents inducing cellular apoptosis while targeting the G2/M phase and Tubulin;Drug Development Research;2023-03-31

2. Six-membered ring systems: pyridines and benzo derivatives;Progress in Heterocyclic Chemistry;2023

3. Characterization of a recently synthesized microtubule-targeting compound that disrupts mitotic spindle poles in human cells;Scientific Reports;2021-12