A new N-methyl thymine derivative comprising a dihydroxyisobutenyl unit as ligand for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK)-Reference-Cited by-同舟云学术

A new N-methyl thymine derivative comprising a dihydroxyisobutenyl unit as ligand for thymidine kinase of herpes simplex virus type 1 (HSV-1 TK)

Published:2011-10 Issue:20 Volume:21 Page:6161-6165
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Krištafor Svjetlana,Novaković Ivana,Gazivoda Kraljević Tatjana,Kraljević Pavelić Sandra,Lučin Pero,Westermaier Yvonne,Pernot Lucile,Scapozza Leonardo,Ametamey Simon M.,Raić-Malić Silvana

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review

2. Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells.

3. A comparison of the antiviral agents 2′-nor-2′-deoxyguanosine and acyclovir: Uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates

4. Synthesis and anti-herpes virus activity of acyclic 2'-deoxyguanosine analogs related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine

5. Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer

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2. Synthesis and in vitro antiproliferative evaluation of novel N-alkylated 6-isobutyl- and propyl pyrimidine derivatives;Bioorganic & Medicinal Chemistry Letters;2014-07

3. Synthesis and Biological Evaluation of a New Acyclic Pyrimidine Derivative as a Probe for Imaging Herpes Simplex Virus Type 1 Thymidine Kinase Gene Expression;Molecules;2013-07-19

4. C-5 Hydroxyethyl and Hydroxypropyl Acyclonucleosides as Substrates for Thymidine Kinase of Herpes Simplex Virus Type 1 (HSV-1 TK): Syntheses and Biological Evaluation;Molecules;2013-05-02

5. Conjugates of 1,2,3-Triazoles and Acyclic Pyrimidine Nucleoside Analogues: Syntheses and X-ray Crystallographic Studies;Current Organic Chemistry;2013-05-01