Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione core-Reference-Cited by-同舟云学术

Synthesis and pharmacological evaluation of novel N-Mannich bases derived from 5,5-diphenyl and 5,5-di(propan-2-yl)imidazolidine-2,4-dione core

Published:2019-08 Issue:16 Volume:29 Page:2387-2392
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Czopek Anna^ORCID,Byrtus Hanna,Zagórska Agnieszka,Rychtyk Joanna,Góra Małgorzata,Sałat Kinga,Rapacz Anna,Obniska Jolanta

Funder

National Institute of Neurological Disorders and Stroke

USA

Jagiellonian University Medical College

ADD

NSC

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference34 articles.

1. Design, synthesis and pharmacological activities of novel N 1-[2-(substituted phenyl)-4-oxo-1,3-thiazolan-3-yl]-2, 2-diphenylacetamides;Husain;Int J Pharm Sci Rev Res,2010

2. Epilepsy: a review of selected clinical syndromes and advances in basic science;Stafstrom;J Cereb Blood Flow Metab,2006

3. Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity;Kenda;J Med Chem,2004

4. Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X);Bialer;Epilepsy Res,2010

5. Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds;Dimmock;Eur J Med Chem,2000

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Current Pharmaceutical Research on the Significant Pharmacophore Mannich bases in Drug Design;Current Topics in Medicinal Chemistry;2023-10

2. Reactive metabolites of the anticonvulsant drugs and approaches to minimize the adverse drug reaction;European Journal of Medicinal Chemistry;2021-12

3. Voltage gated sodium channel inhibitors as anticonvulsant drugs: A systematic review on recent developments and structure activity relationship studies;Bioorganic Chemistry;2021-10

4. Design, Synthesis and Biological Activity of New Amides Derived from 3‐Benzhydryl and 3‐ sec ‐Butyl‐2,5‐dioxo‐pyrrolidin‐1‐yl‐acetic Acid;ChemMedChem;2021-03-02

5. A review on the synthesis and applications of molecules as anticonvulsant drug agent candidates;Medicinal Chemistry Research;2020-07-02