Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA

Author:

Shaikh Mahamadhanif S.,Kanhed Ashish M.,Chandrasekaran Balakumar,Palkar Mahesh B.,Agrawal NikhilORCID,Lherbet Christian,Hampannavar Girish A.,Karpoormath Rajshekhar

Funder

University of KwaZulu-Natal

NRF

NRF-Innovation Post-Doctoral Research Fellowship

NRF-SA

CHPC

UKZN

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference45 articles.

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2. World Health Organization. http://www.who.int/tb/areas-of-work/tb-hiv/en/.

3. Crucial components of Mycobacterium type II fatty acid biosynthesis (Fas-II) and their inhibitors;Duan;FEMS Microbiol. Lett.,2014

4. Isoniazid: a review of characteristics, properties and analytical methods;Fernandes;Crit. Rev. Anal. Chem.,2017

5. First randomised trial of treatments for pulmonary disease caused by M. avium intracellulare, M. malmoense, and M. xenopi in HIV negative patients: rifampicin, ethambutol and isoniazid versus rifampicin and ethambutol;Campbel;Thorax,2001

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