Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists-Reference-Cited by-同舟云学术

Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists

Published:2019-08 Issue:16 Volume:29 Page:2265-2269
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lu Zhonghui,Duan James J.-W.,Xiao Haiyun,Neels James,Wu Dauh-Rurng,Weigelt Carolyn A.,Sack John S.,Khan Javed,Ruzanov Max,An Yongmi,Yarde Melissa,Karmakar Ananta,Vishwakrishnan Sureshbabu,Baratam Venkata,Shankarappa Harisha,Vanteru Sridhar,Babu Venkatesh,Basha Mushkin,Kumar Gupta Arun,Kumaravel Selvakumar,Mathur Arvind,Zhao Qihong,Salter-Cid Luisa M.,Carter Percy H.,Murali Dhar T.G.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

2. Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism

3. The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

4. Targeting the Th17 pathway in psoriasis

5. The psoriasis drugs market

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