Design, synthesis, and biological evaluation of 8-biarylquinolines: A novel class of PDE4 inhibitors-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of 8-biarylquinolines: A novel class of PDE4 inhibitors

Published:2008-02 Issue:4 Volume:18 Page:1407-1412
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Gallant Michel,Chauret Nathalie,Claveau David,Day Stephen,Deschênes Denis,Dubé Daniel,Huang Zheng,Lacombe Patrick,Laliberté France,Lévesque Jean-François,Liu Susana,Macdonald Dwight,Mancini Joseph,Masson Paul,Mastracchio Anthony,Nicholson Donald,Nicoll-Griffith Deborah A.,Perrier Hélène,Salem Myriam,Styhler Angela,Young Robert N.,Girard Yves

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference23 articles.

1. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

2. Keynote review: Phosphodiesterase-4 as a therapeutic target

3. Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and COPD

4. Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor

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