1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity-Reference-Cited by-同舟云学术

1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity

Published:2008-02 Issue:4 Volume:18 Page:1312-1317
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Clark Robin D.,Ray Nicholas C.,Williams Karen,Blaney Paul,Ward Stuart,Crackett Peter H.,Hurley Christopher,Dyke Hazel J.,Clark David E.,Lockey Peter,Devos Rene,Wong Melanie,Porres Soraya S.,Bright Colin P.,Jenkins Robert E.,Belanoff Joseph

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Non-steroidal glucocorticoid receptor antagonists: the race to replace RU-486 for anti-glucocorticoid therapy

2. 2-Benzenesulfonyl-8a-benzyl-hexahydro-2H-isoquinolin-6-ones as selective glucocorticoid receptor antagonists

3. 11β-substituted steroids, an original pathway to antihormones

4. Design of ligands for the glucocorticoid and progestin receptors

5. From RU 38486 towards Dissociated Antiglucocorticoid and Antiprogesterone

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