Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt-Reference-Cited by-同舟云学术

Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt

Published:2017-05 Issue:9 Volume:27 Page:2047-2057
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Kummer David A.,Cummings Maxwell D.,Abad Marta,Barbay Joseph,Castro Glenda,Wolin Ronald,Kreutter Kevin D.,Maharoof Umar,Milligan Cynthia,Nishimura Rachel,Pierce Joan,Schalk-Hihi Celine,Spurlino John,Urbanski Maud,Venkatesan Hariharan,Wang Aihua,Woods Craig,Xue Xiaohua,Edwards James P.,Fourie Anne M.,Leonard Kristi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

2. The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

3. Targeting the Th17 pathway in psoriasis

4. The psoriasis drugs market

5. Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Acid-Promoted Cyclization of α-Azidobenzyl Ketones through C═N Bond Formation: Synthesis of 6-Substituted Quinoline Derivatives;Organic Letters;2024-01-10

2. Modes of action insights from the crystallographic structures of retinoic acid receptor-related orphan receptor-γt (RORγt);European Journal of Medicinal Chemistry;2023-02

3. Statistical Analysis of Protein-Ligand Interaction Patterns in Nuclear Receptor RORγ;Frontiers in Molecular Biosciences;2022-06-15

4. Crystallographic landscape provides molecular insights into the modes of action of diverse ROR-γt modulators;Drug Discovery Today;2022-02

5. The evolution paths of some reprehensive scaffolds of RORγt modulators, a perspective from medicinal chemistry;European Journal of Medicinal Chemistry;2022-01