Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists-Reference-Cited by-同舟云学术

Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists

Published:2014-09 Issue:18 Volume:24 Page:4450-4454
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Sidduri Achyutharao,Budd David C.,Fuentes Maria E.,Lambros Ted,Ren Yonglin,Roongta Vikram,Schoenfeld Ryan C.,Gillespie Paul,Stevenson Christopher S.,Truitt Theresa,Qian Yimin

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference15 articles.

1. Autotaxin inhibitors: a perspective on initial medicinal chemistry efforts

2. Lysophosphatidic acid (LPA) receptors: Signaling properties and disease relevance

3. LPA Receptors: Subtypes and Biological Actions

4. Insights into the pharmacological relevance of lysophospholipid receptors

5. LPA1Receptor Activation Promotes Renal Interstitial Fibrosis

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