Enhancing the therapeutic window for Spectinamide anti-tuberculosis Agents: Synthesis, Evaluation, and activation of phosphate prodrug 3408-Reference-Cited by-同舟云学术

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Enhancing the therapeutic window for Spectinamide anti-tuberculosis Agents: Synthesis, Evaluation, and activation of phosphate prodrug 3408

Published:2024-11 Issue: Volume:112 Page:129934
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Liu Jiuyu,Lukka Pradeep B.,Ektnitphong Victoria A.,Parmar Keyur R.,Wagh Santosh,Lu Yan,Lee Robin B.,Scherbakov Dimitri,Wang Han,Zimmerman Matthew D,Meibohm Bernd,Robertson Gregory T.,Dartois Vêronique,Böttger Erik C.,Lenaerts Anne J.,Lee Richard E.

Funder

American Lebanese Syrian Associated Charities

St. Jude Children's Research Hospital

National Institutes of Health

Publisher

Elsevier BV

Reference16 articles.

1. New agents for the treatment of drug-resistant Mycobacterium tuberculosis;Hoagland;Adv Drug Deliv Rev,2016

2. Anti-tuberculosis treatment strategies and drug development: challenges and priorities;Dartois;Nat Rev Microbiol,2022

3. BPaL approved for multidrug-resistant tuberculosis;Burki;Lancet Infect Dis,2019

4. Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux;Lee;Nat Med,2014

5. Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models;Robertson;J Antimicrob Chemother,2017

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