Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer’s BACE1 inhibitors-Reference-Cited by-同舟云学术

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Triazole-linked reduced amide isosteres: An approach for the fragment-based drug discovery of anti-Alzheimer’s BACE1 inhibitors

Published:2011-07 Issue:13 Volume:21 Page:3992-3996
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Monceaux Christopher J.,Hirata-Fukae Chiho,Lam Polo C.-H.,Totrov Maxim M.,Matsuoka Yasuji,Carlier Paul R.

Funder

Virginia Alzheimer’s and Related Diseases Research Award Fund

Virginia Tech-Georgetown Consortium for Drug Discovery

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference22 articles.

1. Alzheimer Disease in the US Population

2. 2009 Alzheimer's disease facts and figures

3. Alzheimer's Disease: The Amyloid Cascade Hypothesis

4. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

5. BACE-1 inhibition by a series of ψ[CH2NH] reduced amide isosteres

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1. Developments in the chemistry and biology of 1,2,3‐triazolyl‐C‐nucleosides;Archiv der Pharmazie;2023-12-27

2. Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and β-Secretase;ACS Omega;2023-03-16

3. 1, 2, 3-triazole based conjugates-potential cholinesterase (AChE and BuChE) and BACE inhibitors for treatment of Alzheimer;AIP Conference Proceedings;2023

4. Alzheimer's Disease and β-Secretase Inhibition: An Update With a Focus on Computer-Aided Inhibitor Design;Current Drug Targets;2021-08-09

5. Bioactive 1,2,3‐Triazoles: An Account on their Synthesis, Structural Diversity and Biological Applications;The Chemical Record;2021-02-11

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