Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK-Reference-Cited by-同舟云学术

Azaindole N-methyl hydroxamic acids as HIV-1 integrase inhibitors-II. The impact of physicochemical properties on ADME and PK

Published:2010-12 Issue:24 Volume:20 Page:7429-7434
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Tanis Steven P.,Plewe Michael B.,Johnson Ted W.,Butler Scott L.,Dalvie Deepak,DeLisle Dorothy,Dress Klaus R.,Hu Qiyue,Huang Buwen,Kuehler Jon E.,Kuki Atsuo,Liu Wen,Peng Qinghai,Smith Graham L.,Solowiej Jim,Tran Khanh T.,Wang Hai,Yang Anle,Yin Chunfeng,Yu Xiaoming,Zhang Junhu,Zhu Huichun

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. HIV-1 Reverse Transcriptase: A Therapeutical Target in the Spotlight

2. Inhibitors of HIV-1 protease: 10 years after

3. Anti-infectives Clinical progress of HIV-1 integrase inhibitors

4. Novel integrase inhibitors for HIV

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