Discovery of selective, orally bioavailable, N -linked arylsulfonamide Na v 1.7 inhibitors with pain efficacy in mice

Author:

Roecker Anthony J.,Egbertson Melissa,Jones Kristen L.G.,Gomez Robert,Kraus Richard L.,Li Yuxing,Koser Amy Jo,Urban Mark O.,Klein Rebecca,Clements Michelle,Panigel Jacqueline,Daley Christopher,Wang Jixin,Finger Eleftheria N.,Majercak John,Santarelli Vincent,Gregan Irene,Cato Matthew,Filzen Tracey,Jovanovska Aneta,Wang Ying-Hong,Wang Deping,Joyce Leo A.,Sherer Edward C.,Peng Xuanjia,Wang Xiu,Sun Haiyan,Coleman Paul J.,Houghton Andrea K.,Layton Mark E.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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