Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4- d ]imidazole derivatives as microsomal prostaglandin E 2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model-Reference-Cited by-同舟云学术

Tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4- d ]imidazole derivatives as microsomal prostaglandin E 2 synthase-1 (mPGES-1) inhibitors: SAR and in vivo efficacy in hyperalgesia pain model

Published:2017-06 Issue:11 Volume:27 Page:2594-2601
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Muthukaman Nagarajan^ORCID,Tambe Macchindra,Shaikh Mahamadhanif,Pisal Dnyandeo,Deshmukh Sanjay,Tondlekar Shital,Sarode Neelam,Narayana Lakshminarayana,Gajera Jitendra M.,Kattige Vidya G.,Honnegowda Srinivasa,Karande Vikas,Kulkarni Abhay,Behera Dayanidhi,Jadhav Satyawan B.,Gudi Girish S.,Khairatkar-Joshi Neelima,Gharat Laxmikant A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference58 articles.

1. Inhibitors of the Microsomal Prostaglandin E2 Synthase-1 as Alternative to Non Steroidal Anti-Inflammatory Drugs (NSAIDs) – A Critical Review

2. Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

3. Pathway across the blood–brain barrier

4. Fishing for prostanoids: Deciphering the developmental functions of cyclooxygenase-derived prostaglandins

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