Analysis of structure–activity relationships for the ‘B-region’ of N -(3-acyloxy-2-benzylpropyl)- N ′ -[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N -hydroxythiourea analogue with potent analgesic activity-Reference-Cited by-同舟云学术

Analysis of structure–activity relationships for the ‘B-region’ of N -(3-acyloxy-2-benzylpropyl)- N ′ -[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N -hydroxythiourea analogue with potent analgesic activity

Published:2004-05 Issue:9 Volume:14 Page:2291-2297
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lee Jeewoo,Kang Sang-Uk,Choi Hyun-Kyung,Lee Jiyoun,Lim Ju-Ok,Kil Min-Jung,Jin Mi-Kyung,Kim Kang-Pil,Sung Jong-Hyuk,Chung Suk-Jae,Ha Hee-Jin,Kim Young-Ho,Pearce Larry V,Tran Richard,Lundberg Daniel J,Wang Yun,Toth Attila,Blumberg Peter M

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. The diversity in the vanilloid (TRPV) receptor family of ion channels

2. The TRP Channels, a Remarkably Functional Family

3. The capsaicin receptor: a heat-activated ion channel in the pain pathway

4. Cloning and functional expression of a human orthologue of rat vanilloid receptor-1

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