Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy-Reference-Cited by-同舟云学术

Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy

Published:2012-03 Issue:5 Volume:22 Page:1854-1859
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Swahn Britt-Marie,Holenz Jörg,Kihlström Jacob,Kolmodin Karin,Lindström Johan,Plobeck Niklas,Rotticci Didier,Sehgelmeble Fernando,Sundström Marie,Berg Stefan von,Fälting Johanna,Georgievska Biljana,Gustavsson Susanne,Neelissen Jan,Ek Margareta,Olsson Lise-Lotte,Berg Stefan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. Alzheimer's Disease Is a Synaptic Failure

2. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics

3. Purification and cloning of amyloid precursor protein β-secretase from human brain

4. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

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