Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis-Reference-Cited by-同舟云学术

Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis

Published:2012-03 Issue:6 Volume:22 Page:2266-2270
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Andrews Martin J.I.,Andrew Clase J.,Bar Gregory,Tricarico Giovanni,Edwards Paul J.,Brys Reginald,Chambers Mark,Schmidt Wolfgang,MacLeod Angus,Hirst Kim,Allen Vivienne,Birault Veronique,Le Joelle,Harris John,Self Andrew,Nash Kevin,Dixon Graham

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. Rheumatoid arthritis market

2. Therapeutic strategies for rheumatoid arthritis

3. Rheumatoid arthritis: regulation of synovial inflammation

4. Evolving concepts of rheumatoid arthritis

5. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Co-Catalyzed Dual C5/C8–H Bond Functionalization of Imidazo[1,2-a]pyrazines with Disulfides and Grignard Reagents;Organic Letters;2022-10-24

2. The essential role of PRAK in tumor metastasis and its therapeutic potential;Nature Communications;2021-03-19

3. Synthesis and anti-tumor activity of imidazopyrazines as TAK1 inhibitors;European Journal of Medicinal Chemistry;2019-02

4. A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling;ACS Chemical Biology;2018-03-19

5. Pyrazines as Potential Corrosion Inhibitors for Industrial Metals and Alloys: A Review;Journal of Bio- and Tribo-Corrosion;2018-03-13