Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT2C receptor-Reference-Cited by-同舟云学术

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Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT2C receptor

Published:2021-04 Issue: Volume:38 Page:127872
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Schrader Thomas O.,Zhu Xiuwen,Kasem Michelle,Ren Albert,Liu Chunyan,Wu Chunrui,Dang Huong,Le Minh,Gatlin Joel,Chase Kelli,Frazer John,Whelan Kevin T.,Grottick Andrew J.^ORCID,Hutton Clayton,Barden Jeremy,Chen Chuan,Ortiz Alvaro,Feichtinger Konrad,Semple Graeme

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. Multicenter, Placebo-Controlled Trial of Lorcaserin for Weight Management

2. Discovery and Structure−Activity Relationship of (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a Selective Serotonin 5-HT2C Receptor Agonist for the Treatment of Obesity

3. Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients

4. We Need 2C but Not 2B: Developing Serotonin 2C (5-HT2C) Receptor Agonists for the Treatment of CNS Disorders

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Six-membered ring systems: pyridines and benzo derivatives;Progress in Heterocyclic Chemistry;2023

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