Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design-Reference-Cited by-同舟云学术

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Identification of small-molecule inhibitors of the steroidogenic acute regulatory protein (STARD1) by structure-based design

Published:2012-06 Issue:12 Volume:22 Page:4139-4143
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Akula Nagaraju,Midzak Andrew,Lecanu Laurent,Papadopoulos Vassilios

Funder

Canadian Institutes of Health Research

Center grant from Le Fonds de la recherche du Québec-santé

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference24 articles.

1. The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

2. Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter

3. Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states

4. StAR Protein and the Regulation of Steroid Hormone Biosynthesis

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1. Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters;2024-07-22

2. Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1;Nature Communications;2024-06-18

3. Mitochondrial dysfunction in NPC1‐deficiency is not rescued by drugs targeting the glucosylceramidase GBA2 and the cholesterol‐binding proteins TSPO and StARD1;FEBS Letters;2024-02

4. Aryl amino acetamides prevent the development ofPlasmodium falciparumrings via inhibition of the lipid transfer protein PfSTART1;2023-11-04

5. Mitochondrial Cholesterol Metabolites in a Bile Acid Synthetic Pathway Drive Nonalcoholic Fatty Liver Disease: A Revised “Two-Hit” Hypothesis;Cells;2023-05-20

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