A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells-Reference-Cited by-同舟云学术

A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells

Published:2005-10 Issue:20 Volume:15 Page:4550-4554
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Embrey Mark W.,Wai John S.,Funk Timothy W.,Homnick Carl F.,Perlow Debbie S.,Young Steven D.,Vacca Joseph P.,Hazuda Daria J.,Felock Peter J.,Stillmock Kara A.,Witmer Marc V.,Moyer Gregory,Schleif William A.,Gabryelski Lori J.,Jin Lixia,Chen I-Wu,Ellis Joan D.,Wong Bradley K.,Lin Jiunn H.,Leonard Yvonne M.,Tsou Nancy N.,Zhuang Linghang

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference13 articles.

1. Structure and Function of HIV-1 Integrase

2. HIV-1 Integrase: A Target for New AIDS Chemotherapeutics

3. Integrase inhibitors to treat HIV/Aids

4. 4-Aryl-2,4-dioxobutanoic Acid Inhibitors of HIV-1 Integrase and Viral Replication in Cells

5. Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells

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