Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity-Reference-Cited by-同舟云学术

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

Published:2012-11 Issue:21 Volume:22 Page:6705-6711
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Surivet Jean-Philippe,Lange Roland,Hubschwerlen Christian,Keck Wolfgang,Specklin Jean-Luc,Ritz Daniel,Bur Daniel,Locher Hans,Seiler Peter,Strasser Daniel Stefan,Prade Lars,Kohl Christopher,Schmitt Christine,Chapoux Gaëlle,Ilhan Eser,Ekambaram Nadia,Athanasiou Alcibiade,Knezevic Andreja,Sabato Daniela,Chambovey Alain,Gaertner Mika,Enderlin Michel,Boehme Maria,Sippel Virginie,Wyss Pierre

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference42 articles.

1. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

2. Where have all the antibiotic patents gone?

3. Low hanging fruit in infectious disease drug development

4. Why is big Pharma getting out of antibacterial drug discovery?

5. Challenges of Antibacterial Discovery

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