Identification of novel inhibitors of UDP-Glc 4′-epimerase, a validated drug target for african sleeping sickness-Reference-Cited by-同舟云学术

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Identification of novel inhibitors of UDP-Glc 4′-epimerase, a validated drug target for african sleeping sickness

Published:2006-11 Issue:22 Volume:16 Page:5744-5747
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Urbaniak Michael D.,Tabudravu Jioji N.,Msaki Aichi,Matera Kathy Mansfield,Brenk Ruth,Jaspars Marcel,Ferguson Michael A.J.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference18 articles.

1. Antigenic variation in trypansosomes: Secrets surface slowly

2. World, H. O. African Trypanosomiasis, Fact sheet number 259 ed.; WHO publications: Geneva, 2001.

3. The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei

4. N-linked glycans containing linear poly-N-acetyllactosamine as sorting signals in endocytosis in Trypanosoma brucei

5. Trypanosoma brucei Glycoproteins Contain Novel Giant Poly-N-acetyllactosamine Carbohydrate Chains

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1. Molecular characterisation of Entamoeba histolytica UDP-glucose 4-epimerase, an enzyme able to provide building blocks for cyst wall formation;PLOS Neglected Tropical Diseases;2023-08-24

2. Targeted protein degradation might present a novel therapeutic approach in the fight against African trypanosomiasis;European Journal of Pharmaceutical Sciences;2023-07

3. Therapeutic applications of low-molecular-weight thiols and selenocompounds;Redox Chemistry and Biology of Thiols;2022

4. An essential, kinetoplastid-specific GDP-Fuc: β-D-Gal α-1,2-fucosyltransferase is located in the mitochondrion of Trypanosoma brucei;eLife;2021-08-19

5. Eugenia uniflora and Syzygium samarangense extracts exhibit anti-trypanosomal activity: Evidence from in-silico molecular modelling, in vitro, and in vivo studies;Biomedicine & Pharmacotherapy;2021-06

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